A fibrin targeted molecular imaging evaluation of microvascular no‐reflow in acute ischemic stroke
Sign Up to like & getrecommendations! Published in 2022 at "Brain and Behavior"
DOI: 10.1002/brb3.2474
Abstract: To investigate the relationship between fibrin deposition and “no‐reflow” within microcirculation after thrombolysis in acute ischemic stroke (AIS). read more here.
Keywords: molecular imaging; acute ischemic; targeted molecular; ischemic stroke ... See more keywords
Targeted molecular characterization shows differences between primary and secondary myelofibrosis
Sign Up to like & getrecommendations! Published in 2019 at "Genes"
DOI: 10.1002/gcc.22789
Abstract: In BCR‐ABL1‐negative myeloproliferative neoplasms, myelofibrosis (MF) is either primary (PMF) or secondary (SMF) to polycythemia vera or essential thrombocythemia. MF is characterized by an increased risk of transformation to acute myeloid leukemia (AML) and a… read more here.
Keywords: molecular characterization; targeted molecular; shows differences; differences primary ... See more keywords
Modulating SOD1 Folding Landscapes with Targeted Molecular Binders
Sign Up to like & getrecommendations! Published in 2017 at "Biophysical Journal"
DOI: 10.1016/j.bpj.2016.11.928
Abstract: Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease caused by the deterioration of motor neurons that abates essential biological functions and exhibits survival times of 3 - 5 years after diagnosis. One driver of this… read more here.
Keywords: folding landscapes; landscapes targeted; targeted molecular; sod1 ... See more keywords
Abstract 4537: Erdheim Chester disease: A retrospective study characterizing the molecular and pathologic footprints with clinical presentation and comparative outcomes in the present era of targeted molecular targeted therapy
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-4537
Abstract: Erdheim Chester Disease (ECD) is a rare, non-Langerhans cell histiocytic disease, characterized as a neoplastic disorder in 2016. MAP Kinase and PI3-AKT pathway somatic mutations and/or fusion genes have been shown to play a significant… read more here.
Keywords: erdheim chester; disease; diagnosis; therapy ... See more keywords
Targeted Molecular Therapeutic Options for Hepatocellular Carcinoma.
Sign Up to like & getrecommendations! Published in 2020 at "Critical reviews in oncogenesis"
DOI: 10.1615/critrevoncog.2020034985
Abstract: Liver cancer is the 6th leading cause of cancer related deaths in the US even though it ranks 14th in incidence. More men are diagnosed with liver cancer than women, and the number of projected… read more here.
Keywords: hepatocellular carcinoma; hcc; targeted molecular; cancer ... See more keywords
Targeted Molecular Therapeutics for Bladder Cancer—A New Option beyond the Mixed Fortunes of Immune Checkpoint Inhibitors?
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms21197268
Abstract: The fact that there are now five immune checkpoint inhibitor (ICI) monoclonal antibodies approved since 2016 that target programmed cell death protein 1 or programmed death ligand-1 for the treatment of metastatic and refractory bladder… read more here.
Keywords: bladder cancer; molecular therapeutics; targeted molecular; treatment ... See more keywords
Utilizing Genomically Targeted Molecular Data to Improve Patient-Specific Outcomes in Autism Spectrum Disorder
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23042167
Abstract: Molecular biology combined with genomics can be a powerful tool for developing potential intervention strategies for improving outcomes in children with autism spectrum disorders (ASD). Monogenic etiologies rarely cause autism. Instead, ASD is more frequently… read more here.
Keywords: autism spectrum; targeted molecular; utilizing genomically; genomically targeted ... See more keywords