Mitochondria-Targeted New Blue Light-Emitting Fluorescent Molecular Probe
Sign Up to like & getrecommendations! Published in 2019 at "ACS Omega"
DOI: 10.1021/acsomega.8b03331
Abstract: Discovery of a nontoxic fluorescent molecular probe to “light up” specific cellular organelles is extremely essential to understand dynamics of intracellular components. Here, we report a new nontoxic mitochondria-targeted linear bithiazole compound, containing trifluoroacetyl terminal… read more here.
Keywords: mitochondria targeted; fluorescent molecular; targeted new; light ... See more keywords
Bone targeted new zoledronate derivative: design, synthesis, 99mTc-coupling, in-silico study and preclinical evaluation for promising osteosarcoma therapy
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Radiation Biology"
DOI: 10.1080/09553002.2022.2074162
Abstract: Abstract Background: Zoledronate suppresses human sarcomas by blocking the formation of geranylgeranyl diphosphate (GGPP) via inhibiting GGPP synthase. Objectives: Designing of new derivative of dronic acid (1-hydroxy-2-(4-nitro-1H-imidazol-1-yl)ethan-1,1-diyl)bis phosphonic acid), structurally related to zoledronate to be… read more here.
Keywords: osteosarcoma therapy; zoledronate; nitro zoledronate; bone targeted ... See more keywords