Application of Amplicon-Based Targeted NGS Technology for Diagnosis of Drug-Resistant Tuberculosis Using FFPE Specimens
Sign Up to like & getrecommendations! Published in 2022 at "Microbiology Spectrum"
DOI: 10.1128/spectrum.01358-21
Abstract: Amplicon-based targeted NGS technology focuses on a set of gene mutations of known or suspected associations with drug susceptibility in Mycobacterium tuberculosis (MTB). This method offers many benefits, such as low sequencing cost, easy customization,… read more here.
Keywords: technology; amplicon based; targeted ngs; drug ... See more keywords
Abstract 4651: Development of a targeted NGS panel for solid tumor actionable gene targets using multiplex PCR-based enrichment in an integrated fluidic circuit
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Research"
DOI: 10.1158/1538-7445.am2018-4651
Abstract: Introduction: Next-generation sequencing (NGS) has been being rapidly adopted in clinical research to align actionable variants in tumors to targeted therapies or clinical trials. Comprehensive NGS-based tumor profiling assays are an efficient and effective method… read more here.
Keywords: panel; solid tumor; multiplex pcr; cancer ... See more keywords
Reliability of Cell-Free DNA and Targeted NGS in Predicting Chromosomal Abnormalities of Patients With Myeloid Neoplasms
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.923809
Abstract: Introduction Cytogenetic analysis is important for stratifying patients with various neoplasms. We explored the use of targeted next generation sequencing (NGS) in detecting chromosomal structural abnormalities or copy number variations (CNVs) in patients with myeloid… read more here.
Keywords: cell free; targeted ngs; myeloid neoplasms; free dna ... See more keywords
Targeted NGS Yields Plentiful Ultra-Rare Variants in Inborn Errors of Immunity Patients
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DOI: 10.3390/genes12091299
Abstract: Inborn errors of immunity (IEI) include a large group of inherited diseases sharing either poor, dysregulated, or absent and/or acquired function in one or more components of the immune system. Next-generation sequencing (NGS) has driven… read more here.
Keywords: ngs yields; yields plentiful; errors immunity; targeted ngs ... See more keywords
Targeted NGS-Based Analysis of Pneumocystis jirovecii Reveals Novel Genotypes
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Fungi"
DOI: 10.3390/jof8080863
Abstract: Pneumocystis jirovecii is an important etiological agent of pneumonia that is underdiagnosed due to the inability to culture the organism. The 2019 PERCH study identified Pneumocystis as the top fungal cause of pneumonia in HIV-negative… read more here.
Keywords: pneumocystis jirovecii; targeted ngs; pneumocystis; ngs based ... See more keywords