Articles with "targeted peptide" as a keyword



Photo from archive.org

NOP-Targeted Peptide Ligands.

Sign Up to like & get
recommendations!
Published in 2019 at "Handbook of experimental pharmacology"

DOI: 10.1007/164_2018_198

Abstract: The nociceptin/orphanin FQ (N/OFQ)-N/OFQ peptide (NOP) receptor system is widely distributed at both the peripheral and central level where it modulates important biological functions with increasing therapeutic implications. This chapter wants to provide a comprehensive… read more here.

Keywords: targeted peptide; nop targeted; peptide ligands; pharmacology ... See more keywords
Photo from wikipedia

The effects of a mitochondrial targeted peptide (elamipretide/SS31) on BAX recruitment and activation during apoptosis

Sign Up to like & get
recommendations!
Published in 2021 at "BMC Research Notes"

DOI: 10.1186/s13104-021-05613-9

Abstract: Objective Elamipretide (SS31) is a mitochondria-targeted peptide that has reported functions of stabilizing mitochondrial cristae structure and improving mitochondrial bioenergetics. Several studies have documented cell protective features of this peptide, including impairment of intrinsic apoptosis… read more here.

Keywords: bax; apoptosis; elamipretide ss31; activation ... See more keywords
Photo by nci from unsplash

Studies of a novel modified E2F-targeted peptide with activity against castration-resistant prostate cancer.

Sign Up to like & get
recommendations!
Published in 2017 at "Journal of Clinical Oncology"

DOI: 10.1200/jco.2017.35.6_suppl.205

Abstract: 205Background: The E2F family of genes encodes transcription factors that are key to the regulation of a number of target genes, including those encoding cyclins, CDKs, checkpoints regulators, and DNA repair and replication proteins. One… read more here.

Keywords: studies novel; e2f targeted; novel modified; peptide activity ... See more keywords
Photo from wikipedia

Chronic administration of mitochondrion-targeted peptide SS-31 prevents atherosclerotic development in ApoE knockout mice fed Western diet

Sign Up to like & get
recommendations!
Published in 2017 at "PLoS ONE"

DOI: 10.1371/journal.pone.0185688

Abstract: Background Oxidative stress and inflammatory factors are deeply involved in progression of atherosclerosis. Mitochondrion-targeted peptide SS-31, selectively targeting to mitochondrial inner membrane reacting with cardiolipin, has been reported to inhibit ROS generation and mitigate inflammation.… read more here.

Keywords: administration; fed western; mitochondrion targeted; western diet ... See more keywords
Photo from wikipedia

Current status and future of targeted peptide receptor radionuclide positron emission tomography imaging and therapy of gastroenteropancreatic-neuroendocrine tumors

Sign Up to like & get
recommendations!
Published in 2022 at "World Journal of Gastroenterology"

DOI: 10.3748/wjg.v28.i17.1768

Abstract: Theranostics is the highly targeted molecular imaging and therapy of tumors. Targeted peptide receptor radionuclide therapy has taken the lead in demonstrating the safety and effectiveness of this molecular approach to treating cancers. Metastatic, well-differentiated… read more here.

Keywords: receptor radionuclide; imaging therapy; peptide receptor; therapy ... See more keywords