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Published in 2019 at "Handbook of experimental pharmacology"
DOI: 10.1007/164_2018_198
Abstract: The nociceptin/orphanin FQ (N/OFQ)-N/OFQ peptide (NOP) receptor system is widely distributed at both the peripheral and central level where it modulates important biological functions with increasing therapeutic implications. This chapter wants to provide a comprehensive…
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Keywords:
targeted peptide;
nop targeted;
peptide ligands;
pharmacology ... See more keywords
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Published in 2021 at "BMC Research Notes"
DOI: 10.1186/s13104-021-05613-9
Abstract: Objective Elamipretide (SS31) is a mitochondria-targeted peptide that has reported functions of stabilizing mitochondrial cristae structure and improving mitochondrial bioenergetics. Several studies have documented cell protective features of this peptide, including impairment of intrinsic apoptosis…
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Keywords:
bax;
apoptosis;
elamipretide ss31;
activation ... See more keywords
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Published in 2017 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2017.35.6_suppl.205
Abstract: 205Background: The E2F family of genes encodes transcription factors that are key to the regulation of a number of target genes, including those encoding cyclins, CDKs, checkpoints regulators, and DNA repair and replication proteins. One…
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Keywords:
studies novel;
e2f targeted;
novel modified;
peptide activity ... See more keywords
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Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0185688
Abstract: Background Oxidative stress and inflammatory factors are deeply involved in progression of atherosclerosis. Mitochondrion-targeted peptide SS-31, selectively targeting to mitochondrial inner membrane reacting with cardiolipin, has been reported to inhibit ROS generation and mitigate inflammation.…
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Keywords:
administration;
fed western;
mitochondrion targeted;
western diet ... See more keywords
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Published in 2022 at "World Journal of Gastroenterology"
DOI: 10.3748/wjg.v28.i17.1768
Abstract: Theranostics is the highly targeted molecular imaging and therapy of tumors. Targeted peptide receptor radionuclide therapy has taken the lead in demonstrating the safety and effectiveness of this molecular approach to treating cancers. Metastatic, well-differentiated…
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Keywords:
receptor radionuclide;
imaging therapy;
peptide receptor;
therapy ... See more keywords