Articles with "targeted phenyl" as a keyword



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Novel PD-L1-Targeted Phenyl-Pyrazolone Derivatives with Antioxidant Properties

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Published in 2023 at "Molecules"

DOI: 10.3390/molecules28083491

Abstract: Orally-active anticancer small molecules targeting the PD-1/PD-L1 immune checkpoint are actively searched. Phenyl-pyrazolone derivatives with a high affinity for PD-L1 have been designed and characterized. In addition, the phenyl-pyrazolone unit acts as a scavenger of… read more here.

Keywords: targeted phenyl; novel targeted; antioxidant properties; pyrazolone ... See more keywords