Chimeric peptide nanorods for plasma membrane and nuclear targeted photosensitizer delivery and enhanced photodynamic therapy
Sign Up to like & getrecommendations! Published in 2019 at "Applied Materials Today"
DOI: 10.1016/j.apmt.2019.04.017
Abstract: Abstract Tumor therapeutic efficiency is largely determined by the delivery efficacy of therapeutic agent to its final target, especially for photodynamic therapy (PDT). Although plasma membrane or nuclear targeted photosensitizer delivery is considered to be… read more here.
Keywords: nuclear targeted; therapy; photosensitizer delivery; targeted photosensitizer ... See more keywords
A Targeted Photosensitizer Mediated by Visible Light for Efficient Therapy of Bacterial Keratitis.
Sign Up to like & getrecommendations! Published in 2021 at "Biomacromolecules"
DOI: 10.1021/acs.biomac.1c00461
Abstract: Bacterial keratitis is a serious bacterial infection of the cornea that can cause sight loss in severe cases because of the sharp decline of efficacious antibiotics. Herein, a targeted photosensitizer based on BODIPY severing as… read more here.
Keywords: bacterial keratitis; targeted photosensitizer; photosensitizer mediated; therapy ... See more keywords
A novel tumor and mitochondria dual-targeted photosensitizer showing ultra-efficient photodynamic anticancer activities.
Sign Up to like & getrecommendations! Published in 2019 at "Chemical communications"
DOI: 10.1039/c8cc09456j
Abstract: We designed and synthesized a simple, but highly effective photosensitizer (G-Mito-Pc), which can precisely target the mitochondria of epidermal growth factor receptor (EGFR)-overexpressing cancer cells, to achieve dual targeting function at both cell and organelle… read more here.
Keywords: novel tumor; targeted photosensitizer; mitochondria dual; tumor mitochondria ... See more keywords