Articles with "targeted protac" as a keyword



Photo by nci from unsplash

Abstract PR09: KRAS-targeted PROTAC degraders are broadly efficacious against KRAS-dependent tumor models

Sign Up to like & get
recommendations!
Published in 2023 at "Molecular Cancer Research"

DOI: 10.1158/1557-3125.ras23-pr09

Abstract: KRAS is genomically altered in about one third of all human tumors. Due to its central role in oncogenesis, many attempts have been made in the last four decades to drug mutant KRAS, either directly… read more here.

Keywords: kras dependent; targeted protac; mutant kras; kras targeted ... See more keywords