Bone-targeted pH-responsive cerium nanoparticles for anabolic therapy in osteoporosis
Sign Up to like & getrecommendations! Published in 2021 at "Bioactive Materials"
DOI: 10.1016/j.bioactmat.2021.04.038
Abstract: Antiresorptive drugs are widely used for treatment of osteoporosis and cancer bone metastasis, which function mainly through an overall inhibition of osteoclast. However, not all osteoclasts are “bone eaters”; preosteoclasts (pOCs) play anabolic roles in… read more here.
Keywords: bone targeted; responsive cerium; bone; targeted responsive ... See more keywords
A GalNAc-modified CaCO3 nano-immunomodulator for targeted and responsive immunotherapy against orthotopic liver cancer.
Sign Up to like & getrecommendations! Published in 2024 at "Chemical communications"
DOI: 10.1039/d4cc01207k
Abstract: A nano-immunomodulator modified with N-acetylgalactosamine (GalNAc) on calcium carbonate (CaCO3) was prepared for targeted and responsive immunotherapy. And the immunologic adjuvant (CpG ODNs) and doxorubicin (DOX) were released to synergistically improve immune response for treating… read more here.
Keywords: targeted responsive; responsive immunotherapy; liver cancer; nano immunomodulator ... See more keywords
Targeted and responsive biomaterials in osteoarthritis
Sign Up to like & getrecommendations! Published in 2023 at "Theranostics"
DOI: 10.7150/thno.78639
Abstract: Osteoarthritis (OA) is a degenerative disease characterized by loss of articular cartilage and chronic inflammation, involving multiple cellular dysfunctions and tissue lesions. The non-vascular environment and dense cartilage matrix in the joints tend to block… read more here.
Keywords: targeted responsive; drug; medicine; responsive biomaterials ... See more keywords