Mitochondria-targeted supramolecular coordination container encapsulated with exogenous itaconate for synergistic therapy of joint inflammation
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DOI: 10.7150/thno.70623
Abstract: Rationale: Inflammatory macrophages and osteoclasts (OCs) play critical roles in joint inflammation, which feature the excessive production of reactive oxygen species (ROS), resulting in synovial inflammation and bone erosion. Scavenging ROS, especially by modulating mitochondrial… read more here.
Keywords: inflammation; ros scavenging; targeted supramolecular; mitochondria targeted ... See more keywords