Regulating the properties of XQ-2d for targeted therapeutic agents delivery to pancreatic cancer
Sign Up to like & getrecommendations! Published in 2023 at "National Science Review"
DOI: 10.1093/nsr/nwad113
Abstract: Enhanced recognition ability, cell uptake capacity, and biostability are characteristics attributed to aptamer-based targeted anticancer agents, and are possibly associated with increased accumulation at the tumor site, improved therapeutic efficacy, and reduced negative side effects.… read more here.
Keywords: properties targeted; pancreatic cancer; regulating properties; delivery ... See more keywords
Targeted therapeutic strategies for melanoma.
Sign Up to like & getrecommendations! Published in 2023 at "Chinese medical journal"
DOI: 10.1097/cm9.0000000000002692
Abstract: ABSTRACT Melanoma accounts for a small proportion of skin cancers diagnosed each year, but it has a high degree of malignancy and rapid progression, resulting in a short survival period for patients. The incidence of… read more here.
Keywords: therapeutic strategies; melanoma; targeted therapy; targeted therapeutic ... See more keywords
The Promising Evolution of Targeted Therapeutic Strategies in Cancer.
Sign Up to like & getrecommendations! Published in 2021 at "Cancer discovery"
DOI: 10.1158/2159-8290.cd-21-0124
Abstract: The upcoming decade of precision medicine for cancer is moving from the translation of specific genetic findings into clinically relevant improvement to the qualitative analyses of the genomic and immune tumor microenvironment, for an integrated… read more here.
Keywords: therapeutic strategies; cancer; targeted therapeutic; evolution targeted ... See more keywords
Amyloid-beta targeted therapeutic approaches for Alzheimer's disease: long road ahead.
Sign Up to like & getrecommendations! Published in 2022 at "Current drug targets"
DOI: 10.2174/1389450123666220421124030
Abstract: Alzheimer's disease (AD) is a progressive neurodegenerative disorder which is characterized by memory impairment and cognitive decline. The obvious pathological features of AD are still amyloid plaques and neurofibrillary tangles. Development of disease-modifying treatments for… read more here.
Keywords: amyloid beta; beta targeted; disease; alzheimer disease ... See more keywords
Macrophage, a potential targeted therapeutic immune cell for cardiomyopathy
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.908790
Abstract: Cardiomyopathy is a major cause of heart failure, leading to systolic and diastolic dysfunction and promoting adverse cardiac remodeling. Macrophages, as key immune cells of the heart, play a crucial role in inflammation and fibrosis.… read more here.
Keywords: potential targeted; immune cell; therapeutic immune; macrophage potential ... See more keywords
Novel Targeted Therapeutic Strategies for Ewing Sarcoma
Sign Up to like & getrecommendations! Published in 2022 at "Cancers"
DOI: 10.3390/cancers14081988
Abstract: Simple Summary Ewing sarcoma is an uncommon cancer that arises in mesenchymal tissues and represents the second most widespread malignant bone neoplasm after osteosarcoma in children. Therapy has increased the 5-year survival rate in the… read more here.
Keywords: therapeutic strategies; sarcoma; ewing sarcoma; novel targeted ... See more keywords
Emerging Targeted Therapeutic Strategies to Overcome Imatinib Resistance of Gastrointestinal Stromal Tumors
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24076026
Abstract: Gastrointestinal stromal tumors (GISTs) are the most common malignant mesenchymal neoplasms of the gastrointestinal tract. The gold standard for the diagnosis of GISTs is morphologic analysis with an immunohistochemical evaluation plus genomic profiling to assess… read more here.
Keywords: therapeutic strategies; gastrointestinal stromal; stromal tumors; emerging targeted ... See more keywords