Plasmonic Material Engineering for Targeted Therapeutics
Sign Up to like & getrecommendations! Published in 2020 at "Advanced Optical Materials"
DOI: 10.1002/adom.202000616
Abstract: Published in: Advanced Optical Materials DOI: 10.1002/adom.202000616 Publication date: 2020 Document version Publisher's PDF, also known as Version of record Document license: CC BY Citation for published version (APA): Florentsen, C. D., Moreno Pescador, G.… read more here.
Keywords: material engineering; targeted therapeutics; plasmonic material; engineering targeted ... See more keywords
Aquaporin-Targeted Therapeutics: State-of-the-Field.
Sign Up to like & getrecommendations! Published in 2017 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-94-024-1057-0_16
Abstract: Drugs targeting aquaporins have broad potential clinical applications, including cancer, obesity, edema, glaucoma, skin diseases and others. The astrocyte water channel aquaporin-4 is a particularly compelling target because of its role of brain water movement,… read more here.
Keywords: state; state field; aquaporin targeted; targeted therapeutics ... See more keywords
Novel Targeted Therapeutics in Acute Myeloid Leukemia: an Embarrassment of Riches
Sign Up to like & getrecommendations! Published in 2021 at "Current Hematologic Malignancy Reports"
DOI: 10.1007/s11899-021-00621-9
Abstract: Acute myeloid leukemia (AML) is an aggressive malignancy of the bone marrow that has a poor prognosis with traditional cytotoxic chemotherapy, especially in elderly patients. In recent years, small molecule inhibitors targeting AML-associated IDH1, IDH2,… read more here.
Keywords: myeloid leukemia; targeted therapeutics; novel agents; novel targeted ... See more keywords
Targeted Therapeutics for Transthyretin amyloid cardiomyopathy: Time to Move Forward
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cardiac Failure"
DOI: 10.1016/j.cardfail.2019.07.080
Abstract: Introduction Deposition of wild type or mutant transthyretin (TTR) amyloid fibrils causes TTR cardiac amyloidosis (ATTR-CA). Targeted therapeutics (TT) for ATTR-CA include TTR stabilizers (tafamidis, dilfunisal) and oligonucleotide drugs (Revusiran, Patisiran and Inotersen).TTR stabilizers prevent… read more here.
Keywords: targeted therapeutics; patients attr; therapeutics transthyretin; cause mortality ... See more keywords
Small molecules with big roles in microRNA chemical biology and microRNA-targeted therapeutics
Sign Up to like & getrecommendations! Published in 2019 at "RNA Biology"
DOI: 10.1080/15476286.2019.1593094
Abstract: ABSTRACT MicroRNAs (miRNAs) are small, non-coding RNAs that post-transcriptionally regulate gene expression. Aberrant miRNA expression or function have close links with various human diseases. Therefore, therapeutic treatments with disease-associated miRNAs as targets are emerging. However,… read more here.
Keywords: small molecules; targeted therapeutics; big roles; therapeutics small ... See more keywords
MicroRNA-targeted therapeutics for lung cancer treatment
Sign Up to like & getrecommendations! Published in 2017 at "Expert Opinion on Drug Discovery"
DOI: 10.1080/17460441.2017.1263298
Abstract: ABSTRACT Introduction: Lung cancer is one of the leading causes of cancer-related mortality worldwide. MicroRNAs (miRNAs) are endogenous non-coding small RNAs that repress the expression of a broad array of target genes. Many efforts have… read more here.
Keywords: targeted therapeutics; microrna targeted; cancer treatment; lung cancer ... See more keywords
Why targeted therapeutics have provided benefit in psoriasis: looking at IL-17 biology
Sign Up to like & getrecommendations! Published in 2022 at "Expert Review of Clinical Pharmacology"
DOI: 10.1080/17512433.2022.2130758
Abstract: ABSTRACT Introduction Psoriasis is an inflammatory, chronic and immune-mediated disease that can affect the skin and joints. Pro-inflammatory cytokines have a dominant role in the pathogenesis of this heterogeneous disease in which the IL-23/IL-17 axis… read more here.
Keywords: therapeutics provided; targeted therapeutics; benefit psoriasis; provided benefit ... See more keywords
MODL-24. AN ORGANOTYPIC CHUNK CULTURE TECHNIQUE TO STUDY DISEASE MECHANISM AND DEVELOP TARGETED THERAPEUTICS FOR PEDIATRIC ADAMANTINOMATOUS CRANIOPHARYNGIOMA
Sign Up to like & getrecommendations! Published in 2020 at "Neuro-Oncology"
DOI: 10.1093/neuonc/noaa222.597
Abstract: Abstract BACKGROUND Advances in the treatment of Adamantinomatous Craniopharyngioma (ACP) face challenges with translation to clinical study due to the absence of robust culture models of the disease. We developed a technique for culturing human… read more here.
Keywords: technique; adamantinomatous craniopharyngioma; chunk culture; targeted therapeutics ... See more keywords