Advances in Imaging and Targeted Therapies for Recurrent Pericarditis: A Review.
Sign Up to like & getrecommendations! Published in 2022 at "JAMA cardiology"
DOI: 10.1001/jamacardio.2022.2584
Abstract: Importance Pericarditis is the most common form of pericardial disease. Recurrence of pericarditis affects 15% to 30% of patients after the initial episode of pericarditis. Up to 50% of patients with the first recurrence have… read more here.
Keywords: targeted therapies; cardiology; pericarditis; advances imaging ... See more keywords
Variation in Use of Lung Cancer Targeted Therapies Across State Medicaid Programs, 2020-2021
Sign Up to like & getrecommendations! Published in 2023 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2022.52562
Abstract: Key Points Question Does the use of targeted therapies for non–small cell lung cancer (NSCLC) vary across state Medicaid programs? Findings This cross-sectional study found substantial variation in the use of targeted therapies for EGFR-… read more here.
Keywords: state medicaid; state; targeted therapies; medicaid programs ... See more keywords
Advances in drug development for targeted therapies for glioblastoma.
Sign Up to like & getrecommendations! Published in 2020 at "Medicinal research reviews"
DOI: 10.1002/med.21676
Abstract: Glioblastoma is the most aggressive primary brain tumor in adults. The prognosis of patients with primary glioblastoma treated with the current standard of care, tumor resection followed by radiation therapy and auxiliary temozolomide, remains poor.… read more here.
Keywords: drug development; development targeted; advances drug; drug ... See more keywords
Genomic Complexity of Osteosarcoma and Its Implication for Preclinical and Clinical Targeted Therapies.
Sign Up to like & getrecommendations! Published in 2020 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-030-43085-6_1
Abstract: Osteosarcoma is a genomically complex disease characterized by few recurrent single-nucleotide mutations or in-frame fusions. In contrast, structural alterations, including copy number changes, chromothripsis, kataegis, loss of heterozygosity (LOH), and other large-scale genomic alterations, are… read more here.
Keywords: complexity osteosarcoma; genomic complexity; osteosarcoma implication; targeted therapies ... See more keywords
A comprehensive review of genetic alterations and molecular targeted therapies for the implementation of personalized medicine in acute myeloid leukemia
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Molecular Medicine"
DOI: 10.1007/s00109-020-01944-5
Abstract: Acute myeloid leukemia (AML) is an extremely heterogeneous disease defined by the clonal growth of myeloblasts/promyelocytes not only in the bone marrow but also in peripheral blood and/or tissues. Gene mutations and chromosomal abnormalities are… read more here.
Keywords: medicine; myeloid leukemia; molecular targeted; genetic alterations ... See more keywords
First insights for targeted therapies in odontogenic myxoma
Sign Up to like & getrecommendations! Published in 2019 at "Clinical Oral Investigations"
DOI: 10.1007/s00784-019-03107-4
Abstract: Objective Odontogenic myxoma (OM) occasionally responds poorly to surgical treatment. The MAPK pathway is constitutively activated in several neoplasms and we aimed to test if the MAPK pathway is activated in OM, in order to… read more here.
Keywords: odontogenic myxoma; insights targeted; mapk pathway; targeted therapies ... See more keywords
Long-term follow-up assessment of cardiac safety in SAFE-HEaRt, a clinical trial evaluating the use of HER2-targeted therapies in patients with breast cancer and compromised heart function
Sign Up to like & getrecommendations! Published in 2021 at "Breast Cancer Research and Treatment"
DOI: 10.1007/s10549-020-06053-y
Abstract: Purpose HER2-targeted therapies are associated with cardiotoxicity which is usually asymptomatic and reversible. We report the updated cardiac safety assessment of patients with compromised heart function receiving HER2-targeted therapy for breast cancer, enrolled in the… read more here.
Keywords: heart; targeted therapies; her2 targeted; breast cancer ... See more keywords
HDL-Targeted Therapies During Myocardial Infarction
Sign Up to like & getrecommendations! Published in 2019 at "Cardiovascular Drugs and Therapy"
DOI: 10.1007/s10557-019-06865-1
Abstract: It is now apparent that a variety of deleterious mechanisms intrinsic to myocardial infarction (MI) exists and underlies its high residual lethality. Indeed, despite effective coronary patency therapies, ischemia and reperfusion (I/R) injury accounts for… read more here.
Keywords: hdl targeted; therapies myocardial; myocardial infarction; infarction ... See more keywords
Targeted therapies and adverse drug reactions in oncology: the role of clinical pharmacist in pharmacovigilance
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Clinical Pharmacy"
DOI: 10.1007/s11096-018-0653-5
Abstract: Background The majority of adverse drug reactions (ADRs) reported in the summary of product characteristics (SPCs) are based on pivotal clinical trials, performed under controlled conditions and with selected patients. Objectives (1) to observe ADRs… read more here.
Keywords: drug reactions; pharmacist; pharmacovigilance; adverse drug ... See more keywords
The Treatment Landscape and New Opportunities of Molecular Targeted Therapies in Gastroenteropancreatic Neuroendocrine Tumors
Sign Up to like & getrecommendations! Published in 2017 at "Targeted Oncology"
DOI: 10.1007/s11523-017-0532-3
Abstract: Neuroendocrine neoplasms (NENs) are a heterogeneous group of neoplasms that originate from neuroendocrine stem cells and express both neural and endocrine markers. They are found in almost every organ, and while NENs are mostly associated… read more here.
Keywords: treatment landscape; landscape new; treatment; molecular targeted ... See more keywords
Developing Symptom Lists for People with Cancer Treated with Targeted Therapies
Sign Up to like & getrecommendations! Published in 2020 at "Targeted Oncology"
DOI: 10.1007/s11523-020-00769-z
Abstract: Background Targeted therapies (TTs) have revolutionised cancer treatment with their enhanced specificity of action. Compared with conventional therapies, TTs are delivered over a longer period and often have unusual symptom profiles. Patient-reported outcome measures such… read more here.
Keywords: lists people; people cancer; symptom lists; cancer ... See more keywords