Vascular-Targeted Therapy for Systemic Lupus Erythematosus-Associated Vasculitis.
Sign Up to like & getrecommendations! Published in 2023 at "JAMA dermatology"
DOI: 10.1001/jamadermatol.2023.0077
Abstract: This case report describes a woman in her 40s with a medical history of systemic lupus erythematosus with 1 year of tender papules, plaques, and progressive ulcers on her hands and feet. read more here.
Keywords: lupus erythematosus; targeted therapy; systemic lupus; vascular targeted ... See more keywords
Comparative Survival Associated With Use of Targeted vs Nontargeted Therapy in Medicare Patients With Metastatic Renal Cell Carcinoma.
Sign Up to like & getrecommendations! Published in 2019 at "JAMA network open"
DOI: 10.1001/jamanetworkopen.2019.5806
Abstract: Importance Targeted therapies for advanced renal cell carcinoma (RCC) have shown increased tolerability and survival advantages over older treatments in clinical trials, but understanding of real-world survival improvements is still emerging. Objective To compare overall… read more here.
Keywords: targeted therapy; group; nontargeted therapy; targeted nontargeted ... See more keywords
Targeted therapy of advanced parathyroid carcinoma guided by genomic and transcriptomic profiling.
Sign Up to like & getrecommendations! Published in 2023 at "Molecular oncology"
DOI: 10.1002/1878-0261.13398
Abstract: Parathyroid carcinoma (PC) is an ultra-rare malignancy with a high risk of recurrence after surgery. Tumor-directed systemic treatments for PC are not established. We used whole-genome and RNA sequencing in four patients with advanced PC… read more here.
Keywords: targeted therapy; advanced parathyroid; parathyroid carcinoma; therapy advanced ... See more keywords
Bortezomib‐Encapsulated Dual Responsive Copolymeric Nanoparticles for Gallbladder Cancer Targeted Therapy
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Science"
DOI: 10.1002/advs.202103895
Abstract: Gallbladder cancer (GBC) is a rare but the most malignant type of biliary tract tumor. It is usually diagnosed at an advanced stage and conventional treatments are unsatisfactory. As a proteasome inhibitor, bortezomib (BTZ) exhibits… read more here.
Keywords: copolymeric nanoparticles; responsive copolymeric; targeted therapy; btz ... See more keywords
Inhibition of CXCL12/CXCR4 axis as a potential targeted therapy of advanced gastric carcinoma
Sign Up to like & getrecommendations! Published in 2017 at "Cancer Medicine"
DOI: 10.1002/cam4.1085
Abstract: The whole outcome for patients with gastric carcinoma (GC) is very poor because most of them remain metastatic disease during survival even at diagnosis or after surgery. Despite many improvements in multiple strategies of chemotherapy,… read more here.
Keywords: cxcr4 axis; targeted therapy; cxcl12 cxcr4; cxcl12 ... See more keywords
Targeted therapy for colorectal cancer metastases: A review of current methods of molecularly targeted therapy and the use of tumor biomarkers in the treatment of metastatic colorectal cancer
Sign Up to like & getrecommendations! Published in 2019 at "Cancer"
DOI: 10.1002/cncr.32163
Abstract: Despite recent advances in the management of colorectal cancer, metastatic disease remains challenging, and patients are rarely cured. However, a better understanding of the pathways implicated in the evolution and proliferation of cancer cells has… read more here.
Keywords: metastatic colorectal; cancer metastases; targeted therapy; colorectal cancer ... See more keywords
Targeted therapy for lung cancer: Beyond EGFR and ALK
Sign Up to like & getrecommendations! Published in 2023 at "Cancer"
DOI: 10.1002/cncr.34757
Abstract: Precision oncology comprises the set of strategies that aim to design the best cancer treatment based on tumor biology. A recognized subset of patients with non‐small cell lung cancer (NSCLC) harbor actionable genomic aberrations that… read more here.
Keywords: lung cancer; therapy lung; targeted therapy; alk ... See more keywords
Application of Liquid Biopsies in Cancer Targeted Therapy
Sign Up to like & getrecommendations! Published in 2017 at "Clinical Pharmacology and Therapeutics"
DOI: 10.1002/cpt.764
Abstract: As a growing body of evidence demonstrates intertumoral and intratumoral heterogeneity and clonal evolution, both during carcinogenesis and also throughout treatment resulting in acquired drug resistance, the utility of blood‐based assays or “liquid biopsies” is… read more here.
Keywords: application liquid; liquid biopsies; biopsies cancer; targeted therapy ... See more keywords
Special issue “The advance of solid tumor research in China”: Presurgical therapy in the management of local retroperitoneal recurrence of renal cell carcinoma after radical nephrectomy
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Cancer"
DOI: 10.1002/ijc.34173
Abstract: Local retroperitoneal recurrence (RPR) after radical nephrectomy (RN) is rare in patients with renal cell carcinoma (RCC); however, it is associated with poor prognosis and lacks standard treatment. Our study aimed to assess oncological outcomes… read more here.
Keywords: radical nephrectomy; local retroperitoneal; targeted therapy; therapy ... See more keywords
Portopulmonary hypertension practice patterns after liver transplantation
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DOI: 10.1002/lt.26575
Abstract: Portopulmonary hypertension (POPH) is a type of pulmonary arterial hypertension occurring exclusively in those with portal hypertensive liver disease. Liver transplantation (LT) can significantly improve outcomes. Current guidelines counsel against immediate adjustments to targeted therapy… read more here.
Keywords: poph; practice patterns; liver transplantation; targeted therapy ... See more keywords
Molecular targeted therapy-related life-threatening toxicity in patients with malignancies. A systematic review of published cases
Sign Up to like & getrecommendations! Published in 2019 at "Intensive Care Medicine"
DOI: 10.1007/s00134-019-05650-w
Abstract: BackgroundMolecular targeted therapy increased overall and disease-free survival in a wide range of malignancies. Although generally well tolerated compared to chemotherapy, molecular targeted therapy may be associated with adverse events requiring ICU admission. Informing clinicians… read more here.
Keywords: therapy related; targeted therapy; molecular targeted; life threatening ... See more keywords