New Insights on Saporin Resistance to Chemical Derivatization with Heterobifunctional Reagents
Sign Up to like & getrecommendations! Published in 2023 at "Biomedicines"
DOI: 10.3390/biomedicines11041214
Abstract: Saporin is a type 1 ribosome-inactivating protein widely used as toxic payload in the construction of targeted toxins, chimeric molecules formed by a toxic portion linked to a carrier moiety. Among the most used carriers,… read more here.
Keywords: saporin; targeted toxins; heterobifunctional reagents; resistance ... See more keywords
Streptavidin-Saporin: Converting Biotinylated Materials into Targeted Toxins
Sign Up to like & getrecommendations! Published in 2023 at "Toxins"
DOI: 10.3390/toxins15030181
Abstract: Streptavidin-Saporin can be considered a type of ‘secondary’ targeted toxin. The scientific community has taken advantage of this conjugate in clever and fruitful ways using many kinds of biotinylated targeting agents to send saporin into… read more here.
Keywords: saporin converting; saporin; targeted toxins; converting biotinylated ... See more keywords