Recent Advances in Nanoenzymes Based Therapies for Glioblastoma: Overcoming Barriers and Enhancing Targeted Treatment
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Science"
DOI: 10.1002/advs.202413367
Abstract: Glioblastoma multiforme (GBM) is a highly aggressive and malignant brain tumor originating from glial cells, characterized by high recurrence rates and poor patient prognosis. The heterogeneity and complex biology of GBM, coupled with the protective… read more here.
Keywords: targeted treatment; treatment; advances nanoenzymes; based therapies ... See more keywords
Association between timely targeted treatment and outcomes in patients with metastatic HER2‐overexpressing gastroesophageal adenocarcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Cancer"
DOI: 10.1002/cncr.34117
Abstract: Timely targeted treatment initiation can be challenging because additional biomarker testing is needed for eligibility. The authors hypothesized that timely targeted treatment improves survival relative to nontimely initiation in metastatic HER2+ gastroesophageal adenocarcinoma (GEA). read more here.
Keywords: gastroesophageal adenocarcinoma; metastatic her2; timely targeted; targeted treatment ... See more keywords
Early Diagnosis and Targeted Treatment Strategy for Improved Therapeutic Outcomes in Alzheimer's Disease.
Sign Up to like & getrecommendations! Published in 2020 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-030-42667-5_8
Abstract: There have been repeated failures of clinical studies in the development of new efficacious treatments for Alzheimer's disease. This may be due to the fact that Alzheimer's disease is a heterogeneous disorder caused by person-to-person… read more here.
Keywords: alzheimer disease; early diagnosis; disease; targeted treatment ... See more keywords
Targeted Treatment of Age-Related Fibromyalgia with Supplemental Coenzyme Q10.
Sign Up to like & getrecommendations! Published in 2021 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-030-55035-6_5
Abstract: Fibromyalgia is a common chronic pain condition of unknown aetiology, although mitochondrial dysfunction, oxidative stress, and inflammation have been implicated in the pathophysiology of this disorder. Treatment generally involves physiotherapy, anticonvulsants, and antidepressant therapy; however,… read more here.
Keywords: coenzyme q10; treatment; targeted treatment; coq10 ... See more keywords
Study of Folate-Modified Carboxymethyl Chitosan-Sinomenine-Curcumin Nanopolymer for Targeted Treatment of Rheumatoid Arthritis.
Sign Up to like & getrecommendations! Published in 2025 at "Biomacromolecules"
DOI: 10.1021/acs.biomac.4c01701
Abstract: Sinomenine hydrochloride (SH) has been clinically utilized for many years to treat rheumatoid arthritis (RA) in both oral and injectable forms. However, its low bioavailability, poor targeting, high dosage requirements, and side effects, present significant… read more here.
Keywords: targeted treatment; rheumatoid arthritis; carboxymethyl chitosan; sinomenine curcumin ... See more keywords
Targeted Treatment of Yaws With Household Contact Tracing: How Much Do We Miss?
Sign Up to like & getrecommendations! Published in 2018 at "American Journal of Epidemiology"
DOI: 10.1093/aje/kwx305
Abstract: Abstract Yaws is a disabling bacterial infection found primarily in warm and humid tropical areas. The World Health Organization strategy mandates an initial round of total community treatment (TCT) with single-dose azithromycin followed either by… read more here.
Keywords: asymptomatic infections; contact tracing; treatment; epidemiology ... See more keywords
Genotype‐guided targeted treatment of KRAS‐mutated arteriovenous malformations
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the European Academy of Dermatology and Venereology"
DOI: 10.1111/jdv.18165
Abstract: 1966; 34: 827–857 PMID:5330347. 7 Insee. A Mayotte, pr es d’un habitant sur deux est de nationalit e etrang ere. Montrouge, Paris: Insee Premi ere. 2019;1737 [Internet]. French. https:// www.insee.fr/fr/statistiques/3713016 (last accessed 16 November 2021).… read more here.
Keywords: genotype guided; targeted treatment; kras mutated; guided targeted ... See more keywords
Abstract 1882: DXC024, a novel anti-TROP2/EGFR bispecific antibody and tubulysin conjugate, for targeted treatment of highly TROP2- or EGFR-expressing tumors
Sign Up to like & getrecommendations! Published in 2024 at "Cancer Research"
DOI: 10.1158/1538-7445.am2024-1882
Abstract: Antibody drug conjugates (ADCs) which combine the precision of targeted therapy with the cytotoxic effects of chemotherapy have become a promising drug class in cancer therapy. Epidermal growth factor receptor (EGFR) is overexpressed in a… read more here.
Keywords: egfr; targeted treatment; dxc024; anti trop2 ... See more keywords
Promoting CRISPRa for Targeted Treatment of Epilepsy
Sign Up to like & getrecommendations! Published in 2020 at "Epilepsy Currents"
DOI: 10.1177/1535759720935825
Abstract: In Vivo CRISPRa Decreases Seizures and Rescues Cognitive Deficits in a Rodent Model of Epilepsy Colasante G, Qiu Y, Massimino L, et al. Brain. 2020;143(3):891-905. doi:10.1093/brain/awaa045 Epilepsy is a major health burden, calling for new… read more here.
Keywords: epilepsy; promoting crispra; crispra targeted; crispra ... See more keywords
Molecular biomarkers in gastro-esophageal cancer: recent developments, current trends and future directions
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Cell International"
DOI: 10.1186/s12935-018-0594-z
Abstract: Gastro-esophageal adenocarcinomas (GEA) represent a severe global health burden and despite improvements in the multimodality treatment of these malignancies the prognosis of patients remains poor. HER2 overexpression/amplification has been the first predictive biomarker approved in… read more here.
Keywords: gea; biomarker; treatment; gastro esophageal ... See more keywords
Advances in nanomaterial-targeted treatment of acute lung injury after burns
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Nanobiotechnology"
DOI: 10.1186/s12951-024-02615-0
Abstract: To summarize the mechanisms and pathophysiological features of ALI after burn. To classify the targets for the treatment of ALI. Describe the types of nanomedicines used to treat ALI. These findings suggest the prospects and… read more here.
Keywords: treatment ali; targeted treatment; treatment; lung ... See more keywords