The promising role of antibody drug conjugate in cancer therapy: Combining targeting ability with cytotoxicity effectively
Sign Up to like & getrecommendations! Published in 2021 at "Cancer Medicine"
DOI: 10.1002/cam4.4052
Abstract: Traditional cancer therapy has many disadvantages such as low selectivity and high toxicity of chemotherapy, as well as insufficient efficacy of targeted therapy. To enhance the cytotoxic effect and targeting ability, while reducing the toxicity… read more here.
Keywords: drug conjugate; targeting ability; cancer; antibody drug ... See more keywords
Methotrexate-plasmid DNA polyplexes for cancer therapy: Characterization, cancer cell targeting ability and tuned in vitro transfection
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Molecular Liquids"
DOI: 10.1016/j.molliq.2019.111391
Abstract: Abstract Cell targeting is still the most auspicious task in the design/development of innovative drug and gene delivery systems for advanced biomedical applications. To evolve from conventional delivery vectors, which present several limitations, we report… read more here.
Keywords: cell targeting; plasmid dna; cancer; cancer cell ... See more keywords
Tumor-Targeting Ability of Novel Anti-Prostate-Specific Membrane Antigen Antibodies
Sign Up to like & getrecommendations! Published in 2022 at "ACS Omega"
DOI: 10.1021/acsomega.2c04230
Abstract: Patients with prostate-specific membrane antigen (PSMA)-positive tumors can benefit from PSMA-targeted therapy; thus, we have constructed a phage-displayed synthetic antibody library for the production of novel PSMA antibodies with superior PSMA-targeting ability, favoring clinical management.… read more here.
Keywords: prostate specific; targeting ability; membrane antigen; j591 ... See more keywords
In vivo neutron capture therapy of cancer using ultrasmall gadolinium oxide nanoparticles with cancer-targeting ability
Sign Up to like & getrecommendations! Published in 2020 at "RSC Advances"
DOI: 10.1039/c9ra08961f
Abstract: Gadolinium neutron capture therapy (GdNCT) is considered as a new promising cancer therapeutic technique. Nevertheless, limited GdNCT applications have been reported so far. In this study, surface-modified ultrasmall gadolinium oxide nanoparticles (UGNPs) with cancer-targeting ability… read more here.
Keywords: neutron capture; cancer targeting; targeting ability; cancer ... See more keywords
Magnet-Guided Bionic System with LIFU Responsiveness and Natural Thrombus Tropism for Enhanced Thrombus-Targeting Ability
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Nanomedicine"
DOI: 10.2147/ijn.s357050
Abstract: Background Arterial thrombosis is a serious threat to human health. Recently, many thrombus-targeted nanoparticles (NPs) have been constructed for detecting thrombi or monitoring thrombolysis, but their thrombus-targeting performance is limited. Considering this drawback, we designed… read more here.
Keywords: bionic system; system; targeting ability; thrombus targeting ... See more keywords