Proposing novel natural compounds against Alzheimer’s disease targeting acetylcholinesterase
Sign Up to like & getrecommendations! Published in 2023 at "PLOS ONE"
DOI: 10.1371/journal.pone.0284994
Abstract: Alzheimer’s disease (AD) is a neurodegenerative disorder considered as a global public health threat influencing many people. Despite the concerning rise in the affected population, there is still a shortage of potent and safe therapeutic… read more here.
Keywords: alzheimer disease; ic50; novel natural; targeting acetylcholinesterase ... See more keywords
PyPLIF HIPPOS and Receptor Ensemble Docking Increase the Prediction Accuracy of the Structure-Based Virtual Screening Protocol Targeting Acetylcholinesterase
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DOI: 10.3390/molecules27175661
Abstract: In this article, the upgrading process of the structure-based virtual screening (SBVS) protocol targeting acetylcholinesterase (AChE) previously published in 2017 is presented. The upgraded version of PyPLIF called PyPLIF HIPPOS and the receptor ensemble docking… read more here.
Keywords: targeting acetylcholinesterase; virtual screening; protocol targeting; based virtual ... See more keywords