Targeting the Achilles Heel of Mosquito-Borne Viruses for Antiviral Therapy.
Sign Up to like & getrecommendations! Published in 2019 at "ACS infectious diseases"
DOI: 10.1021/acsinfecdis.8b00286
Abstract: Mosquito-borne viruses encompass a wide range of pathogens, such as dengue and Zika viruses, that often cocirculate geographically. These viruses affect hundreds of millions of people worldwide, yet no clinically approved therapy is currently available… read more here.
Keywords: viral infections; mosquito borne; borne viruses; therapy ... See more keywords
Identifying and targeting the Achilles heel of a recalcitrant cancer
Sign Up to like & getrecommendations! Published in 2021 at "Science Translational Medicine"
DOI: 10.1126/scitranslmed.abj6946
Abstract: Targeting replication stress response proteins in small cell lung cancer activates the innate immune cGAS-STING pathway leading to augmentation of immunotherapy’s antitumor response. Targeting replication stress response proteins in small cell lung cancer activates the… read more here.
Keywords: response; heel recalcitrant; identifying targeting; cancer ... See more keywords
Targeting the Achilles’ Heel of Bacteria: Different Mechanisms To Break Down the Peptidoglycan Cell Wall during Bacterial Warfare
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Bacteriology"
DOI: 10.1128/jb.00478-20
Abstract: Bacteria commonly live in dense polymicrobial communities and compete for scarce resources. Consequently, they employ a diverse array of mechanisms to harm, inhibit, and kill their competitors. The cell wall is essential for bacterial survival… read more here.
Keywords: targeting achilles; achilles heel; cell wall; cell ... See more keywords