Articles with "targeting adc" as a keyword



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Abstract 2967: Preclinical development of a B7-H3-targeting ADC with a novel DNA topoisomerase I inhibitor for solid tumors

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Published in 2023 at "Cancer Research"

DOI: 10.1158/1538-7445.am2023-2967

Abstract: Introduction: B7-H3 (CD276) is an immunomodulatory protein of the B7 superfamily molecules, it is overexpressed in a wide range of solid tumors. B7-H3 overexpression often correlates with poor survival and higher tumor grade, it has… read more here.

Keywords: development; dna topoisomerase; solid tumors; novel dna ... See more keywords