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Targeting ADP-ribosylation by PARP inhibitors in acute myeloid leukaemia and related disorders.

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0 Published in 2019 at "Biochemical pharmacology"

DOI: 10.1016/j.bcp.2019.04.019

Abstract: Acute myeloid leukaemia (AML) is a highly heterogeneous disease characterized by uncontrolled proliferation, block in myeloid differentiation and recurrent genetic abnormalities. In the search of new effective therapies, identification of synthetic lethal partners of AML… read more here.

Keywords: adp ribosylation; targeting adp; myeloid leukaemia; ribosylation parp ... See more keywords