Articles with "targeting apoe" as a keyword



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APOE signaling in neurodegenerative diseases: an integrative approach targeting APOE coding and noncoding variants for disease intervention

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Published in 2021 at "Current Opinion in Neurobiology"

DOI: 10.1016/j.conb.2021.02.001

Abstract: APOE (apolipoprotein E) is a key regulator of lipid metabolism and a leading genetic risk factor for Alzheimer's disease. While APOE participates in multiple biological pathways, its roles in diseases are largely due to the… read more here.

Keywords: targeting apoe; integrative approach; intervention; disease ... See more keywords