Targeting Apoptosis Inhibition to Activate Antitumor Immunity.
Sign Up to like & getrecommendations! Published in 2019 at "Trends in immunology"
DOI: 10.1016/j.it.2019.11.002
Abstract: A recent study by Rodriguez-Ruiz et al. suggests that inhibition of apoptotic caspases can augment radiation-induced antitumor immunity, independent of type I IFN. Their findings also highlight caspase-independent cytotoxicity in radiation therapy-induced antitumor immunity, proposing SLC7A2 as… read more here.
Keywords: immunity; antitumor immunity; targeting apoptosis; activate antitumor ... See more keywords
Targeting Apoptosis in AML: Where Do We Stand?
Sign Up to like & getrecommendations! Published in 2022 at "Cancers"
DOI: 10.3390/cancers14204995
Abstract: Simple Summary In patients with acute myeloid leukemia (AML), genetic mutations can cause cells to evade regulated cell death (RCD), resulting in excessive cell proliferation. The best-known form of RCD is apoptosis, which prevents the… read more here.
Keywords: rcd; cell; aml treatment; apoptosis ... See more keywords