Therapeutic reduction of ataxin 2 extends lifespan and reduces pathology in TDP-43 mice
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DOI: 10.1038/nature22038
Abstract: Amyotrophic lateral sclerosis (ALS) is a rapidly progressing neurodegenerative disease that is characterized by motor neuron loss and that leads to paralysis and death 2–5 years after disease onset. Nearly all patients with ALS have… read more here.
Keywords: ataxin; tdp; pathology; therapeutic reduction ... See more keywords