Targeting the PD-1/PD-L1 axis in multiple myeloma: a dream or a reality?
Sign Up to like & getrecommendations! Published in 2017 at "Blood"
DOI: 10.1182/blood-2016-08-731885
Abstract: The programmed cell death protein 1 (PD-1)/programmed cell death ligand 1 (PD-L1) pathway is a negative regulator of immune activation that is upregulated in multiple myeloma and is a critical component of the immunosuppressive tumor… read more here.
Keywords: dream reality; axis multiple; targeting axis; myeloma ... See more keywords
Targeting the PD-1/PD-L1 Axis in Human Vitiligo
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2020.579022
Abstract: Autoreactive CD8+ T cells play a pivotal role in melanocyte destruction in autoimmune vitiligo. Immunotherapy for melanoma often leads to autoimmune side-effects, among which vitiligo-like depigmentation, indicating that targeting immune checkpoints can break peripheral tolerance… read more here.
Keywords: axis human; targeting axis; human vitiligo;
Targeting the PD-1 Axis with Pembrolizumab for Recurrent or Metastatic Cancer of the Uterine Cervix: A Brief Update
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms22041807
Abstract: Even though cervical cancer is partly preventable, it still poses a great public health problem throughout the world. Current therapies have vastly improved the clinical outcomes of cervical cancer patients, but progress in new systemic… read more here.
Keywords: targeting axis; pembrolizumab recurrent; cervical cancer; cancer ... See more keywords