LAUSR

Targeting bacterial nickel transport with aspergillomarasmine A suppresses virulence-associated Ni-dependent enzymes

Sign Up to like & get
recommendations!
0 Published in 2024 at "Nature Communications"

DOI: 10.1038/s41467-024-48232-1

Abstract: Microbial Ni2+ homeostasis underpins the virulence of several clinical pathogens. Ni2+ is an essential cofactor in urease and [NiFe]-hydrogenases involved in colonization and persistence. Many microbes produce metallophores to sequester metals necessary for their metabolism… read more here.

Keywords: nickel transport; targeting bacterial; virulence; dependent enzymes ... See more keywords

Targeting bacterial kinases as a strategy to counteract antibiotic resistance

Sign Up to like & get
recommendations!
0 Published in 2025 at "Communications Chemistry"

DOI: 10.1038/s42004-025-01794-7

Abstract: Antibiotic resistance is rapidly emerging as one of the most critical health threats, with resistant microorganisms progressively diminishing the effectiveness of established antibiotics. As a result, the development of therapeutic approaches that effectively target resistant… read more here.

Keywords: resistance; targeting bacterial; efficacy; antibiotic resistance ... See more keywords

Targeting bacterial growth in biofilm conditions: rational design of novel inhibitors to mitigate clinical and food contamination using QSAR

Sign Up to like & get
recommendations!
0 Published in 2024 at "Journal of Enzyme Inhibition and Medicinal Chemistry"

DOI: 10.1080/14756366.2024.2330907

Abstract: Abstract Antimicrobial resistance (AMR) is a pressing global issue exacerbated by the abuse of antibiotics and the formation of bacterial biofilms, which cause up to 80% of human bacterial infections. This study presents a computational… read more here.

Keywords: growth biofilm; food; targeting bacterial; conditions rational ... See more keywords

Approaches to Targeting Bacterial Biofilms in Cystic Fibrosis Airways

Sign Up to like & get
recommendations!
0 Published in 2021 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms22042155

Abstract: The treatment of lung infection in the context of cystic fibrosis (CF) is limited by a biofilm mode of growth of pathogenic organisms. When compared to planktonically grown bacteria, bacterial biofilms can survive extremely high… read more here.

Keywords: cystic fibrosis; bacterial biofilms; targeting bacterial; approaches targeting ... See more keywords

Targeting Bacterial Nanocellulose Properties through Tailored Downstream Techniques

Sign Up to like & get
recommendations!
0 Published in 2024 at "Polymers"

DOI: 10.3390/polym16050678

Abstract: Bacterial nanocellulose (BNC) is a biodegradable polysaccharide with unique properties that make it an attractive material for various industrial applications. This study focuses on the strain Komagataeibacter medellinensis ID13488, a strain with the ability to… read more here.

Keywords: bnc; nanocellulose properties; bacterial nanocellulose; targeting bacterial ... See more keywords