Gramicidin A-based unimolecular channel: cancer cell-targeting behavior and ion transport-induced apoptosis.
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DOI: 10.1039/d0cc08073j
Abstract: A series of glycoside-peptide conjugates were prepared by engineering at the N-terminus of the natural peptide gramicidin A. The conjugate containing galactose moiety formed a unimolecular transmembrane channel and mediated ion transport to induce apoptosis… read more here.
Keywords: ion transport; cell targeting; cancer cell; cancer ... See more keywords