Dual Targeting Biomimetic Carrier‐Free Nanosystems for Photo‐Chemotherapy of Rheumatoid Arthritis via Macrophage Apoptosis and Re‐Polarization
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DOI: 10.1002/advs.202406877
Abstract: Rheumatoid arthritis (RA) is a common chronic systemic autoimmune disease that often results in irreversible joint erosion and disability. Methotrexate (MTX) is the first‐line drug against RA, but the significant side effects of long‐term administration… read more here.
Keywords: photo chemotherapy; chemotherapy; dual targeting; rheumatoid arthritis ... See more keywords
Organotropic Targeting of Biomimetic Nanoparticles to Treat Lung Disease.
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DOI: 10.1021/acs.bioconjchem.1c00599
Abstract: Active targeting strategies aimed at improving drug homing while reducing systemic toxicity are widely being pursued in the growing field of nanomedicine. While they can be effective, these approaches often require the identification of cell-specific… read more here.
Keywords: organotropic targeting; targeting biomimetic; biomimetic nanoparticles; disease ... See more keywords
Active-targeting biomimetic nanosystem for prostate cancer enhances radiotherapy efficacy by inducing ferroptosis.
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DOI: 10.1186/s12951-025-03879-w
Abstract: Radioresistance and off-target toxicity remain major challenges in prostate cancer (PCa) radiotherapy. Here, we report a biomimetic nanoplatform (Au/MOF-FIN@M-gy1) that synergistically enhances radiation deposition and ferroptosis for precision radiosensitization. By engineering macrophage membranes with prostate-specific… read more here.
Keywords: biomimetic nanosystem; prostate cancer; active targeting; ferroptosis ... See more keywords