Targeting the Brain to Cure Type 2 Diabetes
Sign Up to like & getrecommendations! Published in 2019 at "Diabetes"
DOI: 10.2337/dbi18-0051
Abstract: Present pharmacological treatments of type 2 diabetes aim mainly at increasing insulin secretion by pancreatic β-cells, at improving insulin action on liver, fat, or muscle, and, more recently, at favoring renal glucose elimination. Although efficacious,… read more here.
Keywords: brain cure; targeting brain; type diabetes; neuronal circuits ... See more keywords
Targeting Brain Disease in MPSII: Preclinical Evaluation of IDS-Loaded PLGA Nanoparticles
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms20082014
Abstract: Mucopolysaccharidosis type II (MPSII) is a lysosomal storage disorder due to the deficit of the enzyme iduronate 2-sulfatase (IDS), which leads to the accumulation of glycosaminoglycans in most organ-systems, including the brain, and resulting in… read more here.
Keywords: mpsii preclinical; enzyme; targeting brain; brain disease ... See more keywords