Targeting B Cells and Plasma Cells in Glomerular Disease.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of the American Society of Nephrology : JASN"
DOI: 10.1681/asn.0000000772
Abstract: ABSTRACT Loss of tolerance and the production of self-reactive autoantibodies by the humoral immune system are central to the pathogenesis of many glomerular diseases. These antibodies are produced by plasmablasts and plasma cells, the end-products… read more here.
Keywords: targeting cells; glomerular disease; plasma cells; cells plasma ... See more keywords
Therapies for multiple sclerosis targeting B cells
Sign Up to like & getrecommendations! Published in 2019 at "Croatian Medical Journal"
DOI: 10.3325/cmj.2019.60.87
Abstract: Increasing evidence suggests that B cells contribute both to the regulation of normal autoimmunity and to the pathogenesis of immune mediated diseases, including multiple sclerosis (MS). B cells in MS are skewed toward a pro-inflammatory… read more here.
Keywords: sclerosis; sclerosis targeting; pathology; multiple sclerosis ... See more keywords
Targeting NK Cells for HIV-1 Treatment and Reservoir Clearance
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.842746
Abstract: Combined antiretroviral therapy (cART) can inhibit the replication of human immunodeficiency virus type 1 (HIV-1) and reduce viral loads in the peripheral blood to undetectable levels. However, the presence of latent HIV-1 reservoirs prevents complete… read more here.
Keywords: reservoir clearance; reservoir; targeting cells; cells hiv ... See more keywords
BTN3A Targeting Vγ9Vδ2 T Cells Antimicrobial Activity Against Coxiella burnetii-Infected Cells
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.915244
Abstract: Vγ9Vδ2 T cells have been reported to participate to the immune response against infectious diseases such as the Q fever caused by Coxiella burnetii infection. Indeed, the number and proportion of Vγ9Vδ2 T cells are… read more here.
Keywords: burnetii infected; infection; targeting cells; coxiella burnetii ... See more keywords
Targeting NK Cells to Enhance Melanoma Response to Immunotherapies
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DOI: 10.3390/cancers13061363
Abstract: Simple Summary NK cells are innate immune cells that form one of the initial responses to infections and cancers. There have been increasing number of studies investigating the anti-tumor effects of NK cells. Immunotherapy targeting… read more here.
Keywords: cells enhance; cell biology; biology; enhance melanoma ... See more keywords