Inhibitory targeting cGAS-STING-TBK1 axis: Emerging strategies for autoimmune diseases therapy
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.954129
Abstract: The cGAS-STING signaling plays an integral role in the host immune response, and the abnormal activation of cGAS-STING is highly related to various autoimmune diseases. Therefore, targeting the cGAS-STING-TBK1 axis has become a promising strategy… read more here.
Keywords: sting tbk1; targeting cgas; autoimmune diseases; cgas sting ... See more keywords
Therapeutic Development by Targeting the cGAS-STING Pathway in Autoimmune Disease and Cancer
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2021.779425
Abstract: DNA immune recognition regulation mediated by the cGAS-STING pathway plays an important role in immune functions. Under normal physiological conditions, cGAS can recognize and bind to invading pathogen DNA and activate the innate immune response.… read more here.
Keywords: targeting cgas; cancer; sting pathway; therapeutic development ... See more keywords