Targeting complement-mediated immunoregulation for cancer immunotherapy.
Sign Up to like & getrecommendations! Published in 2018 at "Seminars in immunology"
DOI: 10.1016/j.smim.2018.02.003
Abstract: Complement was initially discovered as an assembly of plasma proteins "complementing" the cytolytic activity of antibodies. However, our current knowledge places this complex system of several plasma proteins, receptors, and regulators in the center of… read more here.
Keywords: mediated immunoregulation; functions complement; targeting complement; complement ... See more keywords
Corrigendum: Targeting Complement Pathways in Polytrauma- and Sepsis-Induced Multiple-Organ Dysfunction
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2019.00994
Abstract: [This corrects the article DOI: 10.3389/fimmu.2019.00543.]. read more here.
Keywords: sepsis induced; polytrauma sepsis; pathways polytrauma; corrigendum targeting ... See more keywords
Targeting the Complement–Sphingolipid System in COVID-19 and Gaucher Diseases: Evidence for a New Treatment Strategy
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms232214340
Abstract: Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2)-induced disease (COVID-19) and Gaucher disease (GD) exhibit upregulation of complement 5a (C5a) and its C5aR1 receptor, and excess synthesis of glycosphingolipids that lead to increased infiltration and activation of… read more here.
Keywords: complement; targeting complement; complement sphingolipid; covid gaucher ... See more keywords