Particle Targeting in Complex Biological Media
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DOI: 10.1002/adhm.201700575
Abstract: Over the past few decades, nanoengineered particles have gained increasing interest for applications in the biomedical realm, including diagnosis, imaging, and therapy. When functionalized with targeting ligands, these particles have the potential to interact with… read more here.
Keywords: particle targeting; complex biological; biological media; protein corona ... See more keywords
Antibody Therapies Targeting Complex Membrane Proteins
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DOI: 10.1016/j.eng.2020.11.013
Abstract: Abstract In analyses of protein families that may serve as drug targets, membrane-associated G-protein-coupled receptors (GPCRs) dominate, followed by ion channels, transporters, and—to a lesser extent—membrane-bound enzymes. However, various challenges put such membrane proteins among… read more here.
Keywords: membrane proteins; antibody therapies; membrane; therapies targeting ... See more keywords