Targeting critical source areas for phosphorus losses: Evaluation with soil testing, farmers’ assessment and modelling
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DOI: 10.1007/s13280-017-0935-5
Abstract: Abstract Diffuse phosphorus (P) losses from arable land need to be reduced in a cost-efficient way, taking into account their temporal and spatial variability. This study, based on 16 farms across southern Sweden, examined possibilities… read more here.
Keywords: critical source; source areas; phosphorus losses; targeting critical ... See more keywords
Synthesis of Novel Kidney-Type Glutaminase Allosteric Inhibitors Targeting the Critical Lys-320 Residue.
Sign Up to like & getrecommendations! Published in 2022 at "ACS medicinal chemistry letters"
DOI: 10.1021/acsmedchemlett.2c00302
Abstract: Reversible allosteric inhibitors of kidney-type glutaminase (GLS1, KGA) showed incomplete inhibition of cancer cell proliferation and poor in vivo efficacy. Here, we investigate some irreversible inhibitors targeting the critical K320 residue responsible for GLS1 biological… read more here.
Keywords: inhibitors targeting; kidney type; targeting critical; type glutaminase ... See more keywords