LAUSR

Targeting Cullin-RING Ubiquitin Ligases and the Applications in PROTACs.

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1 Published in 2020 at "Advances in experimental medicine and biology"

DOI: 10.1007/978-981-15-1025-0_19

Abstract: Cullin-RING ligases (CRLs), the largest family of E3 ubiquitin ligases, have become an attractive target for drug discovery, primarily due to their ability to regulate the degradation of numerous functionally and structurally diverse proteins, thereby… read more here.

Keywords: cullin ring; ring ubiquitin; targeting cullin; ubiquitin ligases ... See more keywords