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Published in 2020 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2020.112116
Abstract: Recent evidence shows that combination of correctors and potentiators, such as the drug ivacaftor (VX-770), can significantly restore the functional expression of mutated Cystic Fibrosis Transmembrane conductance Regulator (CFTR), an anion channel which is mutated…
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Keywords:
targeting different;
cftr structures;
channel;
binding sites ... See more keywords
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Published in 2022 at "Biomaterials science"
DOI: 10.1039/d2bm00076h
Abstract: Osteoclast (OC) abnormalities represent osteoporosis's critical mechanism (OP). OCs undergo multiple processes that range from monocytic to functional. Different drugs target OCs at different developmental stages; however, almost no Suitable drug-targeted delivery systems exist. Therefore,…
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Keywords:
delivery;
delivery system;
system targeting;
nano delivery ... See more keywords
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Published in 2022 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2022.955459
Abstract: Oral cavity is an ideal habitat for more than 1,000 species of microorganisms. The diverse oral microbes form biofilms over the hard and soft tissues in the oral cavity, affecting the oral ecological balance and…
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Keywords:
traditional medicine;
different stages;
natural products;
targeting different ... See more keywords