Targeting drug memory reconsolidation: a neural analysis.
Sign Up to like & getrecommendations! Published in 2020 at "Current opinion in pharmacology"
DOI: 10.1016/j.coph.2020.08.007
Abstract: Addiction can be conceptualised as a disorder of maladaptive learning and memory. Therefore, maladaptive drug memories supporting drug-seeking and relapse behaviours may present novel treatment targets for therapeutic approaches based upon reconsolidation-blockade. It is known… read more here.
Keywords: memory reconsolidation; drug memory; targeting drug; drug ... See more keywords
Assessment of the antitumor activity of a cyclopalladated ferrocene compound assisted by a dual-targeting drug delivery system.
Sign Up to like & getrecommendations! Published in 2018 at "Chemical communications"
DOI: 10.1039/c8cc03308k
Abstract: One cyclopalladated ferrocene compound CP was synthesized, which showed a good cell cytotoxicity. Assisted by a dual-targeting drug delivery system, the anticancer activity of CP to MDA-MB-468 remained unchanged, but the toxicity to non-tumorigenic cell… read more here.
Keywords: targeting drug; cyclopalladated ferrocene; dual targeting; drug ... See more keywords
Advances in Bone-Targeting Drug Delivery: Emerging Strategies Using Adeno-Associated Virus
Sign Up to like & getrecommendations! Published in 2024 at "Human Gene Therapy"
DOI: 10.1089/hum.2024.034
Abstract: The development of bone-targeting drug delivery systems holds immense promise for improving the treatment of skeletal diseases. By precisely delivering therapeutic agents to the affected areas of bone, these strategies can enhance drug efficacy, minimize… read more here.
Keywords: adeno associated; drug delivery; targeting drug; bone targeting ... See more keywords
In Vitro Cytotoxicity and Antitumor Activity of Dual-Targeting Drug Delivery System Based on Modified Magnetic Carbon by Folate
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Nanomaterials"
DOI: 10.1155/2020/7147130
Abstract: A dual-targeting drug delivery system (DTDDS) with magnetic targeting and active targeting was obtained to improve the targeting and drug-loading capacity of magnetic drug nanocarriers. An ultraviolet-visible spectrophotometer and flow cytometry were used to investigate… read more here.
Keywords: targeting drug; delivery system; dual targeting; drug delivery ... See more keywords
An Efficient Cell-Targeting Drug Delivery System Based on Aptamer-Modified Mesoporous Silica Nanoparticles
Sign Up to like & getrecommendations! Published in 2019 at "Nanoscale Research Letters"
DOI: 10.1186/s11671-019-3208-3
Abstract: How to deliver chemotherapeutic drugs efficiently and selectively to tumor cells to improve therapeutic efficacy remains a difficult problem. We herein construct an efficient cell-targeting drug delivery system (Sgc8-MSN/Dox) based on aptamer-modified mesoporous silica nanoparticles… read more here.
Keywords: targeting drug; efficient cell; delivery system; cell targeting ... See more keywords
Angiopep-2-conjugated poly(ethylene glycol)-co- poly(ε-caprolactone) polymersomes for dual-targeting drug delivery to glioma in rats
Sign Up to like & getrecommendations! Published in 2017 at "International Journal of Nanomedicine"
DOI: 10.2147/ijn.s123422
Abstract: The blood–brain barrier is a formidable obstacle for glioma chemotherapy due to its compact structure and drug efflux ability. In this study, a dual-targeting drug delivery system involving Angiopep-2-conjugated biodegradable polymersomes loaded with doxorubicin (Ang-PS-DOX)… read more here.
Keywords: dual targeting; ang dox; targeting drug; glioma ... See more keywords