Early targeting of endoneurial macrophages alleviates the neuropathy and affects abnormal Schwann cell differentiation in a mouse model of Charcot‐Marie‐Tooth 1A
Sign Up to like & getrecommendations! Published in 2022 at "Glia"
DOI: 10.1002/glia.24158
Abstract: We have previously shown that targeting endoneurial macrophages with the orally applied CSF‐1 receptor specific kinase (c‐FMS) inhibitor PLX5622 from the age of 3 months onwards led to a substantial alleviation of the neuropathy in mouse… read more here.
Keywords: charcot marie; cmt1a; model; endoneurial macrophages ... See more keywords