A new uPAR-targeting fluorescent probe for optical guided intracranial surgery in resection of a meningioma—a case report
Sign Up to like & getrecommendations! Published in 2021 at "Acta Neurochirurgica"
DOI: 10.1007/s00701-021-05051-3
Abstract: Meningiomas are benign lesion although anot insignificant number experiences recurrences despite Simpson grade 1 removal. FG001 is a compound with a fluorophore (ICG) that binds to a urokinase-type plasminogen activator receptor (uPAR) and is currently… read more here.
Keywords: fluorescent probe; probe optical; meningioma; targeting fluorescent ... See more keywords
NCL-based mitochondrial-targeting fluorescent probe for the detection of Glutathione in living cells
Sign Up to like & getrecommendations! Published in 2021 at "Chinese Chemical Letters"
DOI: 10.1016/j.cclet.2021.06.033
Abstract: Abstract Glutathione (GSH) plays a critical role in maintaining cellular redox homeostasis in biological system. Mitochondrion is a pivotal organelle for cellular aerobic respiration and its disorder is associated with impaired redox balance, leading to… read more here.
Keywords: fluorescent probe; detection; probe detection; mitochondrial targeting ... See more keywords
An endoplasmic reticulum-targeting fluorescent probe for the imaging of hypochlorous acid in living cells and zebrafishes
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Photochemistry and Photobiology A: Chemistry"
DOI: 10.1016/j.jphotochem.2019.111980
Abstract: Abstract Hypochlorous acid (HClO) plays critical biological roles in living systems, and abnormal accumulation of HClO could cause oxidative stress and lead to tissue damage and a range of diseases. Herein, we present an endoplasmic… read more here.
Keywords: endoplasmic reticulum; hypochlorous acid; targeting fluorescent; reticulum targeting ... See more keywords
Recent progress in organelle-targeting fluorescent probes for the detection of peroxynitrite.
Sign Up to like & getrecommendations! Published in 2024 at "Chemical communications"
DOI: 10.1039/d4cc03452j
Abstract: Peroxynitrite (ONOO-), as an important reactive nitrogen species, plays a pivotal role in the regulation of intracellular redox homeostasis, signal transduction, cell growth and metabolism, and other physiological processes. Organelles are important for regulating ONOO-,… read more here.
Keywords: probes detection; targeting fluorescent; recent progress; fluorescent probes ... See more keywords
385. TRANSLATING MOLECULAR-TARGETING FLUORESCENT PROBES IN OESOPHAGEAL CANCER PRE-CLINICAL MODELS
Sign Up to like & getrecommendations! Published in 2024 at "Diseases of the Esophagus"
DOI: 10.1093/dote/doae057.143
Abstract: Intra-operative molecular imaging (IMI) is an emerging field that utilises tumour-targeting fluorescent probes to improve oncological outcomes. A novel class of probe known as quenched activity-based probes (qABP), developed to measure enzyme activity in-vitro, has… read more here.
Keywords: cancer; targeting fluorescent; fluorescence; fluorescent probes ... See more keywords