Articles with "targeting folding" as a keyword



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Pharmacological inactivation of the prion protein by targeting a folding intermediate

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Published in 2021 at "Communications Biology"

DOI: 10.1038/s42003-020-01585-x

Abstract: Recent computational advancements in the simulation of biochemical processes allow investigating the mechanisms involved in protein regulation with realistic physics-based models, at an atomistic level of resolution. These techniques allowed us to design a drug… read more here.

Keywords: protein; targeting folding; inactivation; prion protein ... See more keywords