Deletion of ligD significantly improves gene targeting frequency in the lignocellulolytic filamentous fungus Penicillium oxalicum.
Sign Up to like & getrecommendations! Published in 2017 at "Fungal biology"
DOI: 10.1016/j.funbio.2017.04.005
Abstract: To improve the gene targeting frequency (GTF) in the lignocellulolytic filamentous fungus Penicillium oxalicum HP7-1, the non-homologous end-joining (NHEJ) gene ligD was deleted. The obtained PoligD deletion mutant ΔPoligD showed no apparent defect in cellulase… read more here.
Keywords: targeting frequency; lignocellulolytic filamentous; deletion; gene targeting ... See more keywords
Local features determine Ty3 targeting frequency at RNA polymerase III transcription start sites.
Sign Up to like & getrecommendations! Published in 2019 at "Genome research"
DOI: 10.1101/gr.240861.118
Abstract: Retroelement integration into host genomes affects both genome structure and function. A goal of a considerable number of investigations is to elucidate host features that influence insertion site selection. The retrotransposon Ty3 of Saccharomyces cerevisiae… read more here.
Keywords: targeting frequency; frequency; rna polymerase; start sites ... See more keywords