Articles with "targeting general" as a keyword



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Therapeutic Targeting of the General RNA Polymerase II Transcription Machinery

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Published in 2020 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms21093354

Abstract: Inhibitors targeting the general RNA polymerase II (RNAPII) transcription machinery are candidate therapeutics in cancer and other complex diseases. Here, we review the molecular targets and mechanisms of action of these compounds, framing them within… read more here.

Keywords: transcription; transcription machinery; rna polymerase; general rna ... See more keywords