Targeting O-GlcNAcylation to develop novel therapeutics.
Sign Up to like & getrecommendations! Published in 2020 at "Molecular aspects of medicine"
DOI: 10.1016/j.mam.2020.100885
Abstract: O-linked β-D-N-acetylglucosamine (O-GlcNAc) is an abundant post-translational modification (PTM) that modifies the serine or threonine residues of thousands of proteins in the nucleus, cytoplasm and mitochondria. Being a major "nutrient sensor" in cells, the O-GlcNAc… read more here.
Keywords: glcnac; novel therapeutics; targeting glcnacylation; develop novel ... See more keywords
Targeting O-GlcNAcylation in ischemic stroke
Sign Up to like & getrecommendations! Published in 2022 at "Neural Regeneration Research"
DOI: 10.4103/1673-5374.335806
Abstract: Ischemic stroke is a common and often devastating disease that primarily affects the elderly. Treatment currently consists predominantly of acute thrombolysis and/ or thrombectomy to restore blood flow. This reperfusion therapy, however, is only accessible… read more here.
Keywords: targeting glcnacylation; stroke; ischemic stroke; glcnacylation ischemic ... See more keywords