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Published in 2018 at "Nature Communications"
DOI: 10.1038/s41467-018-03941-2
Abstract: Glucagon-like peptide-1 receptor (GLP-1R) activation promotes insulin secretion from pancreatic beta cells, causes weight loss, and is an important pharmacological target in type 2 diabetes (T2D). Like other G protein-coupled receptors, the GLP-1R undergoes agonist-mediated endocytosis,…
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Keywords:
agonist;
targeting glp;
efficacy;
receptor trafficking ... See more keywords