TARGETING HEAT SHOCK PROTEIN 90 AND ITS DOWNSTREAM SIGNALING HUBS FOR THE TREATMENT OF MANTLE CELL LYMPHOMA
Sign Up to like & getrecommendations! Published in 2017 at "Hematological Oncology"
DOI: 10.1002/hon.2439_171
Abstract: 21 days. Tumor growth was measured using callipers. Results: PIM1/2/3 were ubiquitously expressed in primary and cultured RS cells but not in healthy donor‐derived peripherial B cells. PIM1/2/3 expression was driven by JAK‐STAT and NFκB… read more here.
Keywords: protein; pim; pim kinases; expression ... See more keywords
Targeting heat shock proteins 90 and 70: A promising remedy for both autoimmune bullous diseases and COVID-19
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.1080786
Abstract: Heat shock proteins (Hsps), including Hsp90 and Hsp70, are intra- and extracellular molecules implicated in cellular homeostasis and immune processes and are induced by cell stress such as inflammation and infection. Autoimmune bullous disorders (AIBDs)… read more here.
Keywords: shock proteins; targeting heat; autoimmune bullous; heat shock ... See more keywords