Phenomenon of Endothelial Antibody Capture: Principles and Potential for Locoregional Targeting of Hepatic Tumors
Sign Up to like & getrecommendations! Published in 2018 at "Hepatology"
DOI: 10.1002/hep.30072
Abstract: The systemic drug circulation represents a source of adverse effects during tumor targeting. We studied the binding efficacy of endothelium‐specific antibodies after a very short contact with an antigen target, along with assessing the intravascular… read more here.
Keywords: hepatic tumors; phenomenon endothelial; targeting hepatic; antibody ... See more keywords
Therapeutic Targeting of Hepatic ACSL4 Ameliorates Non-alcoholic Steatohepatitis in Mice.
Sign Up to like & getrecommendations! Published in 2021 at "Hepatology"
DOI: 10.1002/hep.32148
Abstract: Globally, NAFLD is one of the most common liver disorders, with an estimated prevalence rate of more than 30% in men and 15% in women, and an even higher prevalence in people with type 2… read more here.
Keywords: targeting hepatic; acsl4 ameliorates; acsl4; hepatic acsl4 ... See more keywords
Whole grains-derived functional ingredients against hyperglycemia: targeting hepatic glucose metabolism.
Sign Up to like & getrecommendations! Published in 2023 at "Critical reviews in food science and nutrition"
DOI: 10.1080/10408398.2023.2183382
Abstract: Type 2 diabetes mellitus (T2DM) is characterized by the dysregulation of glucose homeostasis, resulting in hyperglycemia. However, concerns have been raised about the safety and efficacy of current hypoglycemic drugs due to undesirable side effects.… read more here.
Keywords: glucose metabolism; hepatic glucose; targeting hepatic; whole grains ... See more keywords
Abstract 4139399: Targeting Hepatic Complement C3 Attenuates Pulmonary Arterial Hypertension Phenotype in Rodents
Sign Up to like & getrecommendations! Published in 2024 at "Circulation"
DOI: 10.1161/circ.150.suppl_1.4139399
Abstract: Background: Pulmonary arterial hypertension (PAH) is a severe condition characterized by pulmonary vascular remodelling leading to right ventricle failure. Emerging evidence highlights inflammation as crucial pathogenic factor of PAH. Members of the complement pathway have… read more here.
Keywords: pah; arterial hypertension; complement pathway; targeting hepatic ... See more keywords
Rosavin Ameliorates Hepatic Inflammation and Fibrosis in the NASH Rat Model via Targeting Hepatic Cell Death
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms231710148
Abstract: Background: Non-alcoholic fatty liver disease (NAFLD) represents the most common form of chronic liver disease that urgently needs effective therapy. Rosavin, a major constituent of the Rhodiola Rosea plant of the family Crassulaceae, is believed… read more here.
Keywords: cell death; hepatic cell; via targeting; targeting hepatic ... See more keywords