Targeting HER2 in Advanced Breast Cancer.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7219-7_4
Abstract: Human epidermal growth factor receptor 2 (HER2) is a human oncogene that is amplified in approximately 20% of breast cancers, and portends a worse prognosis if not treated with anti-HER2 agents. The advent of targeted… read more here.
Keywords: anti her2; her2; targeting her2; breast cancer ... See more keywords
p95HER2–T cell bispecific antibody for breast cancer treatment
Sign Up to like & getrecommendations! Published in 2018 at "Science Translational Medicine"
DOI: 10.1126/scitranslmed.aat1445
Abstract: T cell bispecific antibodies against an isoform of HER2 effectively target many HER2-expressing tumors but not normal tissues. Fine-tuning HER2 targeting HER2 receptor tyrosine kinase is frequently overexpressed in breast and gastric cancer. HER2-overexpressing tumors… read more here.
Keywords: targeting her2; p95her2; breast; cell bispecific ... See more keywords