Articles with "targeting hippo" as a keyword



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The Hippo in the room: Targeting the Hippo signalling pathway for osteosarcoma therapies

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Published in 2020 at "Journal of Cellular Physiology"

DOI: 10.1002/jcp.29967

Abstract: Osteosarcoma (OS) is a primary malignant bone tumour which usually occurs in children and adolescents. OS is primarily a result of chromosomal aberrations, a combination of acquired genetic changes and, hereditary, resulting in the dysregulation… read more here.

Keywords: hippo signalling; hippo room; targeting hippo; room targeting ... See more keywords
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Targeting the Hippo Pathway in Gastric Cancer and Other Malignancies in the Digestive System: From Bench to Bedside

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Published in 2022 at "Biomedicines"

DOI: 10.3390/biomedicines10102512

Abstract: The Hippo pathway is an evolutionally conserved signaling cascade that controls organ size and tissue regeneration under physiological conditions, and its aberrations have been well studied to promote tumor initiation and progression. Dysregulation of the… read more here.

Keywords: targeting hippo; hippo pathway; cancer; gastric cancer ... See more keywords