Targeting host lipid flows: Exploring new antiviral and antibiotic strategies
Sign Up to like & getrecommendations! Published in 2019 at "Cellular Microbiology"
DOI: 10.1111/cmi.12996
Abstract: Bacteria and viruses pose serious challenges for humans because they evolve continuously. Despite ongoing efforts, antiviral drugs to treat many of the most troubling viruses have not been approved yet. The recent launch of new… read more here.
Keywords: antiviral antibiotic; flows exploring; lipid flows; host ... See more keywords
Targeting IL-13 as a Host-Directed Therapy Against Ulcerative Colitis
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2018.00395
Abstract: The role of interleukin-13 in mediating ulcerative colitis remains under scrutiny. Compelling evidence from both man and mouse suggests that IL-13 not only contributes to the pathology associated with disease but is also involved in… read more here.
Keywords: directed therapy; therapy ulcerative; host directed; colitis ... See more keywords
Targeting the Host Mitochondria as a Novel Human Cytomegalovirus Antiviral Strategy
Sign Up to like & getrecommendations! Published in 2023 at "Viruses"
DOI: 10.3390/v15051083
Abstract: Human cytomegalovirus (HCMV) exploits host mitochondrial function to promote viral replication. HCMV gene products have been described to directly interact and alter functional or structural aspects of host mitochondria. Current antivirals against HCMV, such as… read more here.
Keywords: mitochondrial function; host mitochondrial; targeting host; human cytomegalovirus ... See more keywords