Mucosal targeting in IgA nephropathy targeting the gut associated lymphoid tissue
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DOI: 10.1111/nep.14365
Abstract: IgA nephropathy is a mucosally driven disease and new therapeutic approaches are specifically targeting the mucosal production of IgA in the hope that this will lead to a reduction in circulating IgA immune complexes and… read more here.
Keywords: nephropathy targeting; mucosal; mucosal targeting; targeting iga ... See more keywords
B cell targeting in IgA nephropathy
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DOI: 10.1111/nep.14367
Abstract: The “multi‐hit theory/4‐hit theory” pathogenesis hypothesis is widely accepted and IgA nephropathy (IgAN) is understood to be a disease originating from Hit 1, galactose deficient IgA1 (GdIgA1). The chronic repetitive activation of the complement pathway… read more here.
Keywords: targeting iga; cell targeting; iga nephropathy; gdiga1 ... See more keywords