Articles with "targeting igf1r" as a keyword



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miR-100-5p Inhibits Malignant Behavior of Chordoma Cells by Targeting IGF1R

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Published in 2020 at "Cancer Management and Research"

DOI: 10.2147/cmar.s252185

Abstract: Purpose Our research aimed to illuminate the role of miR-100-5p in chordoma and potential mechanism. Materials and Methods We used microRNA array analysis to explore differentially expressed miRNAs in chordoma tissue and then verified by… read more here.

Keywords: chordoma cells; 100 inhibits; chordoma; targeting igf1r ... See more keywords
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Let-7b acts as a tumor suppressor in osteosarcoma via targeting IGF1R

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Published in 2019 at "Oncology Letters"

DOI: 10.3892/ol.2018.9793

Abstract: MicroRNAs serve crucial functions in cancer progression by inhibiting the translation of target genes and causing mRNA degradation. However, the underlying regulatory mechanism of Let-7b in osteosarcoma (OS) has not, to the best of our… read more here.

Keywords: acts tumor; let acts; igf1r let; let ... See more keywords